Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·Why finding breast cancer targets may not be enough for CAR-T therapy
Review or Meta-AnalysisA 2026 review examines HER2, EGFR and MUC1 as breast cancer targets, plus tumor diversity and safety risks. Its abstract does not establish patient benefit.
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Evidence date ·Two roles for sugar-based particles in cancer immunotherapy
Review or Meta-AnalysisA review contrasts β-glucan, which can engage immune-cell receptors, with adaptable dextran carriers. Mouse studies and clinical uses answer different questions.
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Evidence date ·Why might clearing aging cells call for a different immune attack than cancer?
Review or Meta-AnalysisA 2026 review surveys engineered T-cell studies in liver and heart models, then examines target overlap and safety barriers to clearing aging cells in people.
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Evidence date ·A damaged disc may need its tissue-building cells back
Review or Meta-AnalysisA review proposes clearing aging disc cells, restoring healthy gene activity, then adding replacement cells. Human disc regeneration remains unproven.
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Evidence date ·How inflammation, fuel use and aging may stiffen the heart
Peer-Reviewed PaperA review connects inflammation, fuel use and aging to impaired heart filling. Some treatments ease symptoms or reduce hospitalizations; survival benefit remains unproven.
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Evidence date ·Could preservation time help assess a donor liver?
Review or Meta-AnalysisMachine perfusion offers a way to study senescence and test targeted treatments in donor livers. Whether this helps transplant patients remains unproven.
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Evidence date ·When immune cleanup helps repair—and when it stalls
Review or Meta-AnalysisRemoving some senescent cells slowed mouse wound healing; removing others sped it up. Immune-based treatments for senescence remain unproven in people.
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Evidence date ·What must happen for magnetic particles to help immune cells respond to tumors?
Review or Meta-AnalysisA June 2026 review links magnetic heating and iron chemistry to immune changes in experiments. Mouse studies offer clues, while delivery and safety remain hurdles.
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Evidence date ·Why did prolonged cell resetting damage mouse livers, and what did an antioxidant change?
Peer-Reviewed PaperIn mice, sustained cell reprogramming injured the liver. An antioxidant delayed death while measured reprogramming markers remained; regeneration was not shown.
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Evidence date ·Can tumor immune signals change without rewriting DNA?
Review or Meta-AnalysisA review surveys ways to activate immune-related genes in cancer cells without changing DNA sequence. The work is preclinical, and delivering the tools remains a hurdle.