Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·Can aging skin benefit from clearing cells that stopped dividing or quieting their signals?
Peer-Reviewed PaperA research synthesis compares drugs that clear senescent cells with treatments that quiet their signals, including what human skin findings measured.
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Evidence date ·What grounded sleep could reveal about cognition and personal experience
Clinical TrialA registered study proposes grounded sleep, cognitive tests, and a questionnaire; its plan is not evidence of an Alzheimer’s treatment.
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Evidence date ·A proposed fisetin add-on aims to improve hip-surgery treatment
Clinical TrialA 2021 registry proposes fisetin before and after hip surgery with platelet-rich plasma and losartan, testing added benefit, safety, and biological markers.
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Evidence date ·What did creatine add to a 12-week exercise and diet program?
Clinical TrialTracked over timeA 12-week trial in adults aged 45–65 found lean-tissue and strength gains with creatine, but mixed memory results. Exercise participation was self-selected.
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Evidence date ·A creatine combination changed tissue and movement measures in older adults
Clinical TrialTracked over timeA 2021 pilot compared guanidinoacetate plus creatine with placebo in 21 older adults, finding higher tissue creatine and changed mobility outcomes.
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Evidence date ·A proposed way to make behavioral sleep therapy easier to follow for Veterans with cognitive difficulties
Clinical TrialA planned pilot pairs insomnia therapy with memory-support strategies for Veterans with mild cognitive impairment; benefits remain untested.
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Evidence date ·SYNERGIC@Home plans to test remote exercise and cognitive training
Clinical TrialA planned 64-person trial pairs home exercise with cognitive training to study participation, preferences and adherence—not proven dementia prevention.
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Evidence date ·Could clearing senescent cells help diabetes without weight loss?
Review or Meta-AnalysisA 2021 review links senescent-cell clearance to better metabolism in obese mice and early human fat-tissue changes, without proving patient benefit.
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Evidence date ·How daily timing connects to recycling inside brain cells
Review or Meta-AnalysisA July 2021 review links clock-gene experiments with sleep-related waste transport and cellular recycling; patient benefit remains unproven.
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Evidence date ·The preservation interval may offer a chance to treat a donated kidney
Review or Meta-AnalysisA 2021 review explains how cold and warm kidney perfusion could carry treatments, what animal studies found, and why donor and recipient results differ.