Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·Why clearing cells could matter to a heart that cannot easily replace muscle
Review or Meta-AnalysisA 2021 review compares mouse heart-function results, repair timing and drug toxicities, while showing why senolytics are not yet a patient treatment.
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Evidence date ·A proposed Hanoi pilot brings four kinds of dementia care together
Clinical TrialA planned Hanoi pilot combines four kinds of care and compares them with regular advice, separating practical delivery from possible resident benefits.
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Evidence date ·How BioFINDER-Sleep will connect sleep symptoms with Parkinson’s over time
Clinical TrialTracked over timeA registered study pairs overnight sleep testing, brain and heart imaging, and biological samples to ask whether patterns can anticipate later symptoms.
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Evidence date ·A planned supplement trial will examine sleep and thinking in mild cognitive impairment
Clinical TrialTracked over timeA 2023 registry entry describes a planned citicoline-versus-placebo pilot in mild cognitive impairment, tracking sleep, thinking and biomarkers.
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Evidence date ·Associations between sleep and amyloid deposits varied by brain region in older adults
Peer-Reviewed PaperTracked over timeAmong 4,425 older adults without cognitive impairment, sleep duration was linked to brain amyloid levels. The study cannot show whether changing sleep helps.
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Evidence date ·How aging immune cells and tumor surroundings shape treatment in older adults
Review or Meta-AnalysisTracked over timeA 2026 review examines cancer immunotherapy outcomes in older adults and preclinical ways to clear senescent cells or induce senescence in tumors.
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Evidence date ·Should cancer treatment remove impaired T cells or restore them?
Review or Meta-AnalysisTracked over timeA review explains why aged T cells may lose the ability to multiply yet retain tumor-killing activity, and how restoration differs from removal.
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Evidence date ·When aging changes the immune neighborhood around a tumor
Review or Meta-AnalysisTracked over timeA 2021 review reports mixed findings on age and cancer immunotherapy. Removing senescent cells to improve treatment was still an unproven proposal.
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Evidence date ·How blood and urine tests could probe a cellular role in long COVID
Clinical TrialA 2021 registry planned blood and urine tests for senescence, inflammation and auto-antibodies to assess whether a future drug trial could be justified.
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Evidence date ·NiteCAPP asks whether web-based insomnia care can fit family caregiving
Clinical TrialNiteCAPP’s planned study would assess online insomnia therapy for rural dementia caregivers, with assessments after treatment and at six and twelve months.