Research area
Brain Health & Neurology
Brain function, neurological disease, dementia and neurological treatment and care.
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Evidence date ·Could Otago exercise support everyday thinking in dementia?
Clinical TrialA six-month pilot is designed to test whether Otago exercise added to usual care improves decision-making and task management in people with dementia.
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Evidence date ·A whole-day view of activity, sleep, and thinking in later life
Clinical TrialA planned study asks how activity types, sleep quality and sleep duration relate to memory and planning. It does not establish cognitive benefits.
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Evidence date ·In residential care, enjoying a robot is not the same as feeling better
Clinical TrialA registry-described study tests a 10-week companion-robot program against no PARO sessions, measuring loneliness and symptoms at weeks 10 and 14.
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Evidence date ·How researchers plan to compare older patients’ recovery stories with cognitive tests
Clinical TrialA registered Swedish study plans interviews, cognitive tests and recovery measures to compare older patients’ experiences after joint replacement.
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Evidence date ·What a Hai Duong program asks about living with dementia
Clinical TrialA study plan in Hai Duong, Vietnam, asks whether exercise and cognitive training add to dementia education. The registry description provides no results.
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Evidence date ·A brainstem arousal hub is linked to slow sleep rhythms in Alzheimer’s disease
Peer-Reviewed PaperTracked over timeBrain scans and overnight recordings in 58 adults linked a brainstem sleep hub to slow-wave strength, not simply time spent in deep sleep.
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Evidence date ·How an overactive arousal circuit shaped sleep in amyloid-model mice
Peer-Reviewed PaperTracked over timeIn mice modeling Alzheimer’s disease, an arousal circuit was overactive. Drugs improved selected sleep measures, but benefits for people remain unproven.
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Evidence date ·Why the locus coeruleus matters during sleep and Alzheimer’s research
Review or Meta-AnalysisTracked over timeA 2022 review weighs animal experiments and human observations on how a brainstem wakefulness system might link disrupted sleep and Alzheimer’s disease.
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Evidence date ·Why researchers proposed removing stressed support cells in amyotrophic lateral sclerosis
Review or Meta-AnalysisA 2021 review considers removing senescent support cells in ALS, weighing evidence from other diseases against risks to motor neurons and blood cells.
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Evidence date ·An Ontario study brings dementia research into daily life
Clinical TrialAn Ontario study pairs 7–10 days of wearable data with blood samples and questionnaires to study aging and explore potential uses in detection and care.