Research area
Brain Health & Neurology
Brain function, neurological disease, dementia and neurological treatment and care.
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Evidence date ·Can individualized care improve memory and thinking in nine months?
Clinical TrialA registered randomized trial tests whether care tailored to extensive personal data can improve memory and thinking beyond standard care over nine months.
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Evidence date ·After cognitive impairment begins, what do treatment patterns show?
Peer-Reviewed PaperA 126-person study compared blood-pressure and sleep-apnea treatment patterns after cognitive impairment began, finding associations that remain observational.
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Evidence date ·How Taiwanese older adults’ sleep and activity may relate to thinking
Clinical TrialA Taiwanese registry plan will measure sleep, activity, and cognition in 150 older adults, but a relationship would not prove dementia prevention.
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Evidence date ·Could faulty protein recycling disrupt sleep in Alzheimer’s mice?
Peer-Reviewed PaperTracked over timeResearchers separated true sleep from quiet inactivity, located early clearance problems in sleep-regulating neurons, and tested recovery in control mice.
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Evidence date ·How damaged sleep circuits may let Alzheimer’s proteins build up
Review or Meta-AnalysisTracked over timeA 2023 review links disrupted sleep circuits and protein maintenance in Alzheimer’s, but whether sleep treatment can slow cognitive decline remains unproven.
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Evidence date ·How exercise may change brain protein clearance in Alzheimer’s
Review or Meta-AnalysisA 2023 review links exercise to brain fluid clearance and memory in mice. Whether enhancing clearance can benefit people with Alzheimer’s remains unproven.
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Evidence date ·A sensory chair under study for dementia residents and care staff
Clinical TrialA randomized nursing-home study tests rocking, music, and touch for dementia-related behaviors while asking whether care staff’s daily work also benefits.
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Evidence date ·Walking, photographs and shared support for older Black dementia caregivers
Clinical TrialA registry describes three-person walks with historical photos for older Black dementia caregivers, plus assessments of health, fit and cultural relevance.
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Evidence date ·What creatine might reveal about inflammation in cerebral palsy
Review or Meta-AnalysisA 2022 opinion paper proposes testing creatine in cerebral palsy models, separating inflammation in muscle and other tissues from inflammation in the brain.
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Evidence date ·Can a six-week day-care program help with sleep problems and distress when dementia starts early?
Clinical TrialA planned study pairs needs assessment with six weekly day-care sessions for sleep problems and distress in young-onset dementia. Benefits remain unproven.