Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·What have marine compounds shown for the aging liver?
Review or Meta-AnalysisA 2026 review reports less liver fat and injury in animal models and improved metabolic measures in early human studies. Neither shows reversal of liver aging.
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Evidence date ·How might aging immune defenses leave the brain more vulnerable?
Review or Meta-AnalysisThe review traces how weaker immune responses, senescent brain cells and barrier changes may sustain inflammation. Human findings remain mostly associative.
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Evidence date ·How metabolism and aging blood vessels affect each other
Review or Meta-AnalysisA 2026 review traces how glucose and fat metabolism affect aging vessel walls and other organs, and compares exercise and drug findings. Vascular improvement is not proof of reversal.
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Evidence date ·Could engineered immune cells help treat breast cancer?
Review or Meta-AnalysisThe review explains how CAR-T cells are designed and why breast tumors pose added hurdles. Its discussion of trials does not establish clinical benefit.
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Evidence date ·Could SIRT1 activation help preserve memory as the brain ages?
Review or Meta-AnalysisA 2026 review surveys mouse studies linking SIRT1 activity to cognition and discusses resveratrol, metformin and exercise. Human memory benefits remain unproven.
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Evidence date ·What changed after the older mice received the drug?
Peer-Reviewed PaperOlder mice with Alzheimer’s-related mutations slept more during their usual rest period by week five of MW151 treatment. Whether it helps people is unknown.
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Evidence date ·How lingering stressed cells may connect kidney injury to scarring
Review or Meta-AnalysisPersistent senescent cells may promote kidney scarring. Human data are observational; animal experiments suggest a causal role, but patient benefit is unproven.
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Evidence date ·How signals around a broken bone change as it heals
Review or Meta-AnalysisA March 2026 review maps signals associated with senescence across fracture repair. Mouse drug results are encouraging, but patient benefit remains unproven.
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Evidence date ·Could targeting stressed brain cells help people with neurodegenerative disease?
Review or Meta-AnalysisA review describes signs of senescence in different brain cells across Alzheimer’s, Parkinson’s and multiple sclerosis. A five-person pilot found no significant cognitive change.
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Evidence date ·Could natural killer cells help older adults stay healthy?
Review or Meta-AnalysisA 2026 review connects aging-related changes in natural killer cells with immune surveillance. Tests and preventive treatments still need validation.