Research area
Cancer Biology
How cancers develop, evolve and interact with their surroundings and the immune system.
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Evidence date ·What can Merkel cell carcinoma’s viral or ultraviolet origin reveal about outlook?
Review or Meta-AnalysisA 2021 review reports a more favorable outlook for virus-linked Merkel cell tumors than for tumors tied to ultraviolet-induced genetic damage.
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Evidence date ·Why does MSI-high matter more in some colorectal cancer stages?
Review or Meta-AnalysisA 2021 meta-analysis linked high microsatellite instability with less spread overall; survival differences were clearest in stages II and III.
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Evidence date ·How do breast cancer risk genes relate to treatment when tumors vary?
Review or Meta-AnalysisA 2021 survey covers BRCA1’s roles in cell division and DNA-damage response, and why tumor diversity complicates breast cancer treatment research.
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Evidence date ·Why AIM2 can point cancer treatment in opposite directions
Review or Meta-AnalysisA January 2026 review traces how AIM2 can restrain tumor growth or fuel inflammation in different settings. It does not show that targeting AIM2 improves patient outcomes.
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Evidence date ·How cancer reaches distant tissues and why treatment can struggle there
Review or Meta-AnalysisA 2025 review describes how cancer cells change the way they move and why distant tissues can hinder drug delivery. It surveys clinical and experimental treatments.
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Evidence date ·How inflammation can help lung tumors evade immune attack
Review or Meta-AnalysisA 2023 review explains how IL-1β-driven inflammation may suppress immunity in NSCLC, what trials found, and why patient-selection markers remain unresolved.
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Evidence date ·Why researchers may stop cancer cells before trying to clear them
Review or Meta-AnalysisTracked over timeA 2024 review explains how growth-arrested cancer cells alter nearby tissue, why responses differ by tumor, and what blocks safe selective clearance.
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Evidence date ·How growth-arrested cells may reshape lymphatic routes used by cancer
Review or Meta-AnalysisTracked over timeA 2023 review explains how vessel entry, changing lymph flow, and weakened immune defenses may connect senescence with cancer spread and treatment.
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Evidence date ·How treatment-altered support cells and collagen may reshape one another
Review or Meta-AnalysisTracked over timeA review explains how fibroblasts may reshape collagen after head and neck cancer therapy, why senescence markers can mislead, and where treatments might act.
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Evidence date ·How treatment-altered support cells influenced prostate and ovarian cancer cells
Peer-Reviewed PaperTracked over timeIn cell cultures, signals from chemotherapy-treated support cells increased cancer-cell movement. Clearing those support cells reduced the effect.