Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·Could Otago exercise support everyday thinking in dementia?
Clinical TrialA six-month pilot is designed to test whether Otago exercise added to usual care improves decision-making and task management in people with dementia.
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Evidence date ·How aged marrow immune cells affect distant organs in mice
Peer-Reviewed PaperTracked over timeA mouse study traces age-related dysfunction from aged marrow immune cells to released vesicles, then contrasts fenofibrate tests in mice with medical-record associations.
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Evidence date ·How aged blood can trigger cellular aging in young mice
Peer-Reviewed PaperTracked over timeOld blood increased senescence markers in young mice. Treating old donors reduced several responses, but did not reverse deficits in old recipients.
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Evidence date ·A whole-day view of activity, sleep, and thinking in later life
Clinical TrialA planned study asks how activity types, sleep quality and sleep duration relate to memory and planning. It does not establish cognitive benefits.
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Evidence date ·How cancer treatment can stop tumors and strain healthy tissue
Review or Meta-AnalysisA 2022 review examines whether targeting senescent cells could ease lasting harm from cancer treatment, and why mouse findings do not establish human benefit.
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Evidence date ·What researchers plan to learn from six months of metformin in people with chronic obstructive pulmonary disease who do not have diabetes
Clinical TrialTracked over timeA planned metformin study in older people with chronic lung disease and no diabetes focuses on safety, tolerability and aging-related blood markers.
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Evidence date ·Removing harmful airway cells or changing their activity
Review or Meta-AnalysisTracked over timeA 2023 review links airway-cell damage, failed mitochondrial cleanup and inflammatory signals; benefits for chronic obstructive lung disease remain unproven.
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Evidence date ·How stalled cell renewal may sustain chronic lung injury
Review or Meta-AnalysisTracked over timeA June 2022 review links senescent cells to COPD’s repair and inflammation problems, while separating cell removal from signal control.
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Evidence date ·In residential care, enjoying a robot is not the same as feeling better
Clinical TrialA registry-described study tests a 10-week companion-robot program against no PARO sessions, measuring loneliness and symptoms at weeks 10 and 14.
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Evidence date ·Can changing sleep spindles, patterns of sleep brain activity, help older adults?
Clinical TrialA proposed home study asks whether brain stimulation can change sleep spindles in healthy older adults. Benefits for memory remain unproven.