Research area
Diagnostics & Medical Imaging
Clinical tests, imaging and patient monitoring. Cancer-specific detection belongs under Cancer Detection & Prevention.
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Evidence date ·What a brief forehead recording found about blood and brain fluid in aging and Alzheimer’s
Peer-Reviewed PaperForehead recordings found a stronger inverse relationship between blood-volume and inferred brain-fluid signals in Alzheimer’s than in healthy older adults.
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Evidence date ·What does an improved MRI score reveal about cognitive decline?
Peer-Reviewed PaperA revised MRI score showed slightly stronger correlations with cognitive assessments in a 50-sample test set. Its sleep-quality correlation was weak and nonsignificant.
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Evidence date ·What can a new brain-fluid scan reveal about waste clearance?
Peer-Reviewed PaperMRI showed regional differences in how brain-fluid motion varied with heartbeat and breathing. Visual stimulation changed it locally; waste removal was not measured.
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Evidence date ·Three ways to calculate a brain MRI score—and what each changes
Peer-Reviewed PaperIn MRI data from 172 older adults, head pitch was linked to the uncorrected DTI-ALPS score but not to two adjusted versions. None directly measures brain fluid flow.
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Evidence date ·What can a GFAP blood result reveal about brain changes?
Review or Meta-AnalysisA 2025 review examines how GFAP, a protein in brain support cells, reaches blood, why tests may miss some forms, and what head injury and Alzheimer’s studies show.
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Evidence date ·Enlarged spaces on brain scans offer an uncertain clue to small vessel disease
Review or Meta-AnalysisA 2025 review compares visible spaces around brain vessels with MRI measures of water movement and blood flow. None is a validated test of waste clearance.
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Evidence date ·Can experimental scans locate senescent cells in arthritic joints?
Review or Meta-AnalysisAn enzyme-sensitive MRI and PET approach highlights senescence-related signals in cartilage and animal joints, but patient testing remains unresolved.
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Evidence date ·A two-year observational study asks who may develop early Alzheimer’s-related cognitive impairment
Clinical TrialA planned study asks whether adding blood tests and wearable data to genetic information helps predict early cognitive impairment over two years.
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Evidence date ·A planned Alzheimer’s study pairs laboratory sleep tests and adds home recordings
Clinical TrialA planned Alzheimer’s study will compare sleep-stage results from simultaneous lab tests and include three home nights. No results are posted.
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Evidence date ·When dementia care teams can see residents’ sleep measurements
Clinical TrialA registered four-week study asks whether sharing sleep measurements with dementia care teams changes care documentation and residents’ sleep quality.