Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·How could senescent-cell medicines improve everyday health?
Review or Meta-AnalysisAn NIA workshop report examines a small lung-disease study and why markers, coexisting illnesses, and other medicines shape senolytic trials.
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Evidence date ·How changing culture temperature made an engineered kidney cell model useful for testing drugs aimed at senescent cells
Peer-Reviewed PaperTracked over timeResearchers shifted engineered human kidney cells from 33°C to 37°C and found that some drugs reduced viability more in cells with senescence-like features.
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Evidence date ·How nondividing cells can still affect kidney health
Review or Meta-AnalysisTracked over timeMouse experiments removing p16-positive cells, plus a 2021 review of senolytics and donor-kidney perfusion, show why human benefit remains uncertain.
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Evidence date ·What a three-way study of sleep, exercise, and dementia risk can show
Clinical TrialA registered study compares sleep support, exercise, and both over 12 weeks. Its protocol describes planned measurements, not demonstrated dementia prevention.
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Evidence date ·How cells that stop dividing might connect aging to severe COVID-19
Review or Meta-AnalysisA 2021 review connects immune aging, senescent-cell signals and ACE2’s two roles, then weighs how far evidence from other viruses can support treatment ideas.
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Evidence date ·When the sound around a person with dementia becomes part of care
Clinical TrialA 2021 trial registration proposes personalized soundscapes for dementia care, measuring distress, sleep, stress and quality of life without claiming results.
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Evidence date ·Can caregivers stick with a self-administered hypnosis program?
Clinical TrialA 2021 registry describes proposed randomized feasibility research comparing self-administered hypnosis with sham white noise hypnosis and planned caregiver sleep measures.
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Evidence date ·A pilot asks whether clearing senescent cells could improve walking after childhood cancer
Clinical TrialA 2021 registry pilot pairs two short treatments intended to clear senescent cells with walking-speed and blood-marker checks at days 60 and 150.
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Evidence date ·Aging immunity may need new cells and healthy support tissues
Review or Meta-AnalysisAn August 2025 review links declining T-cell renewal to thymus and lymph-node changes and asks how treatment findings translate to ordinary aging.
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Evidence date ·How aging biology may shape physical and cognitive function after cancer
Review or Meta-AnalysisA 2021 review connects aging biology, nutrition, and functional measures to cancer survivorship research—without promising a ready treatment.