Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·A tumor biopsy gets a control phase and a drug test in the same well
Clinical TrialResearchers tested living tumor fragments from biopsies by measuring immune activity before and after checkpoint drugs. The approach still needs clinical validation.
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Evidence date ·How aging brain immune cells can help or hinder new neurons
Review or Meta-AnalysisA 2026 review explains how microglia can help or hinder new neurons and surveys ways to track neurogenesis or alter local immune signals. Human benefits remain unproven.
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Evidence date ·Why AIM2 can point cancer treatment in opposite directions
Review or Meta-AnalysisA January 2026 review traces how AIM2 can restrain tumor growth or fuel inflammation in different settings. It does not show that targeting AIM2 improves patient outcomes.
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Evidence date ·How aging-cell signals and faltering cleanup affect the heart and arteries
Review or Meta-AnalysisA 2026 review examines senescent cells in plaques and aging hearts, animal treatment findings, and why benefits for patients remain unproven.
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Evidence date ·A younger cell is not yet a repaired tissue
Review or Meta-AnalysisSmall molecules can change cell identity and age-related features in lab and animal studies. Human findings involve related compounds, not cell reprogramming.
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Evidence date ·What changed in fat and immune cells after obese-donor plasma?
Peer-Reviewed PaperMice given obese-donor plasma had higher aging-related markers in fat and immune cells than controls; weight and two plasma cytokines did not differ significantly.
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Evidence date ·Which stress-altered heart cells should remain after a heart attack?
Review or Meta-AnalysisA December 2025 review weighs cell-clearing studies against evidence that some stressed heart cells help limit scarring. Human findings remain observational.
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Evidence date ·Could problems with brain drainage help explain memory decline?
Review or Meta-AnalysisA 2025 review examines whether venous pressure could hinder brain fluid clearance. Reports of cognitive improvement after stenting come from other patient groups.
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Evidence date ·Could cell-by-cell maps guide more selective aging treatments?
Review or Meta-AnalysisA December 2025 review compares animal cell maps with human intervention studies. Cell-targeted therapies remain proposals, not proven ways to extend healthspan.
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Evidence date ·What would engineered immune cells have to overcome inside a breast tumor?
Review or Meta-AnalysisA 2025 review examines how uneven tumor markers and dense tissue may hinder CAR-T cells in breast cancer. Early patient reports have not established lasting benefit.