Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·What can body mass index tell us about immunotherapy outcomes?
Review or Meta-AnalysisTracked over timeA review of 20 studies linked higher body mass index to longer survival and more immune-related side effects during immunotherapy; results varied by cancer and sex.
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Evidence date ·What lignin, xylan and cellulose bring to drug carriers
Review or Meta-AnalysisA 2021 review describes far greater drug release from one xylan carrier with rat cecal and colonic contents, and compares lignin and cellulose carriers.
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Evidence date ·Why can linking immune cells to cancer cells work differently by setting?
Review or Meta-AnalysisA 2021 review contrasts catumaxomab’s use for cancer-related abdominal fluid with a separate intravenous study that reported serious liver toxicity.
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Evidence date ·Why have T-cell engagers advanced further in blood cancers than solid tumors?
Review or Meta-AnalysisTracked over timeBy linking T cells to cancer cells, engagers have shown benefit in leukemia and myeloma. A 2026 review explains why solid tumors are harder to reach and target safely.
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Evidence date ·How does one lipid particle link a T cell to a tumor cell?
Peer-Reviewed PaperTracked over timeA lipid particle with CD3- and HER2-binding fragments helped T cells kill HER2-positive tumor cells in models; a third binder targets PD-L1.
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Evidence date ·One T-cell bridge can carry three ways to recognize myeloma
Peer-Reviewed PaperTracked over timeCompared with single-target versions, three-target particles increased myeloma-cell killing in marrow-like cultures and delayed tumor progression in mice.
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Evidence date ·How do immune cells reach a tumor inside a chip?
Review or Meta-AnalysisA 2021 review explains why a vessel-like barrier matters for tumor chips and how image analysis can track immune-cell behavior as conditions change.
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Evidence date ·Could a persistent rash during immunotherapy matter before blisters?
Review or Meta-AnalysisA review of 58 cases found that an itchy eruption sometimes preceded blisters, and the skin disease often interrupted cancer immunotherapy.
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Evidence date ·A lung biopsy can show which immune cells sit beside a tumor
Review or Meta-AnalysisA 2021 review shows how multiple stains reveal which cells carry PD-L1 and where immune cells sit in lung tumors. Earlier studies linked both patterns to survival.
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Evidence date ·Why a blood-cancer treatment faces different conditions inside solid tumors
Review or Meta-AnalysisCAR T cells can treat some B cell cancers. The review shows why solid tumors pose different hurdles: selecting a safe target, entering the tumor, and staying active inside it.