Research area
Brain Health & Neurology
Brain function, neurological disease, dementia and neurological treatment and care.
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Evidence date ·How Alzheimer’s may disrupt the circuits that keep us asleep and awake
Review or Meta-AnalysisA 2021 review examines how tau-related damage to sleep and wake circuits may contribute to fragmented nights and daytime sleepiness in Alzheimer’s.
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Evidence date ·Can targeting senescent cells improve memory after chronic stress in mice?
Peer-Reviewed PaperA 2021 mouse study tested memory after chronic stress, then used drugs targeting senescent cells; brain and blood measures leave the mechanism open.
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Evidence date ·When living brain cells stop dividing but keep sending signals
Review or Meta-AnalysisA 2021 review connects senescent cells with Alzheimer’s models and brain tumors, but does not establish that experimental clearance benefits patients.
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Evidence date ·How aging strains the systems that keep brain connections adaptable
Review or Meta-AnalysisA 2021 review connects brain adaptability with energy supply and cellular recycling. Animal findings do not establish ways to prevent dementia in humans.
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Evidence date ·Could tailored activities and caregiver support ease distress in hospitalized older adults?
Clinical TrialA randomized human trial compares usual medication with tailored activities and caregiver education; its registry record lists the symptom measure but no posted results.
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Evidence date ·How rehabilitation wards could recognize memory and thinking needs
Clinical TrialAn Italian diagnostic study screens rehabilitation patients for memory and thinking difficulties, then uses deeper tests and 12-month follow-up to study change.
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Evidence date ·A six-week test of online lessons and symptom tracking for dementia caregivers
Clinical TrialA registered Taiwan study tests six weeks of online lessons and symptom tracking with alternating assignment, comparing caregiver confidence, symptoms and burden.
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Evidence date ·What an online caregiver group will test for Lewy body dementia
Clinical TrialA planned eight-week text group for Lewy body dementia caregivers will be compared with educational materials, with depression checked at week 8 and six months.
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Evidence date ·How wakefulness signals may link disturbed sleep and Alzheimer’s changes
Review or Meta-AnalysisA June 4, 2026 review explains how orexin may link broken sleep with Alzheimer’s proteins, weighing receptor-blocking drugs and preclinical ginseng research.
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Evidence date ·How a critical illness can affect brain function after the crisis
Review or Meta-AnalysisA June 2026 narrative review examines how inflammation may affect memory, why vulnerability varies, and what separates a target from a proven treatment.