Research area
Health & Longevity
Human health, disease, treatment and aging. The largest corpus area supports distinct cancer, neurological and therapeutic navigation.
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Evidence date ·Can a six-week day-care program help with sleep problems and distress when dementia starts early?
Clinical TrialA planned study pairs needs assessment with six weekly day-care sessions for sleep problems and distress in young-onset dementia. Benefits remain unproven.
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Evidence date ·How stopped cells can interfere with the body’s response to insulin
Review or Meta-AnalysisA 2022 review connects senescent fat cells to insulin resistance, compares cell-clearing strategies, and explains what early human findings can show.
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Evidence date ·Why compare two forms of brain stimulation for sleep problems in Alzheimer’s disease
Clinical TrialA registry outlines a trial of two forms of electrical brain stimulation for sleep problems in Alzheimer's disease; it reports no treatment results.
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Evidence date ·Why researchers are comparing heart images with neurological assessments
Clinical TrialA registry study pairs radioactive-tracer heart imaging with neurological assessments across sleep, movement and memory changes; its diagnostic value remains to be tested.
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Evidence date ·Removing persistent senescent cells or quieting their harmful signals
Review or Meta-AnalysisA 2022 review compares drugs that remove senescent cells with those that quiet their signals, from human tissue findings to platelet toxicity.
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Evidence date ·Could targeting cells that stopped dividing preserve health with age?
Review or Meta-AnalysisA 2022 review compares drugs that quiet senescent-cell signals with drugs that kill them, and explains what early patient findings measured.
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Evidence date ·Could Otago exercise support everyday thinking in dementia?
Clinical TrialA six-month pilot is designed to test whether Otago exercise added to usual care improves decision-making and task management in people with dementia.
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Evidence date ·How aged marrow immune cells affect distant organs in mice
Peer-Reviewed PaperTracked over timeA mouse study traces age-related dysfunction from aged marrow immune cells to released vesicles, then contrasts fenofibrate tests in mice with medical-record associations.
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Evidence date ·How aged blood can trigger cellular aging in young mice
Peer-Reviewed PaperTracked over timeOld blood increased senescence markers in young mice. Treating old donors reduced several responses, but did not reverse deficits in old recipients.
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Evidence date ·A whole-day view of activity, sleep, and thinking in later life
Clinical TrialA planned study asks how activity types, sleep quality and sleep duration relate to memory and planning. It does not establish cognitive benefits.