Research area
Cell & Gene Therapy
Therapeutic cells, gene-based treatments and biological regeneration, including engineered immune cells for cancer.
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Evidence date ·How engineered T cells find cancer and why control matters
Review or Meta-AnalysisA January 2021 review explains how CAR T cells combine antibody-based targeting with T-cell activation, while solid-tumor use depends on controlling effects outside tumors.
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Evidence date ·How engineered immune cells might clear senescent cells while preserving repair
Review or Meta-AnalysisA review explains how engineered T cells might clear senescent cells in mice, why persistence differs from drug dosing, and what complicates treatment in people.
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Evidence date ·What engineered immune cells recognize in cells that stop dividing
Review or Meta-AnalysisEngineered T cells can kill senescent cells in culture, but benefits for age-associated disease remain unproven in people.